A signature of enhanced lipid metabolism, lipid peroxidation and aldehyde stress in therapy-induced senescence. Flor AC, Wolfgeher D, Wu D, Kron SJ. Nature Cell Death Discovery. 2017 Oct 30. doi: 10.1038/cddiscovery.2017.75.

Simple strategies to enhance discovery of acetylation post-translational modifications by quadrupole-orbitrap LC-MS/MS. Manning AJ, Lee J, Wolfgeher DJ, Kron SJ, Greenberg JT. Biochim Biophys Acta. 2017 Oct 16. doi: 10.1016/j.bbapap.2017.10.006.

HMG-CoA reductase inhibition delays DNA repair and promotes senescence after tumor irradiation. Efimova EV, Ricco N, Labay E, Mauceri HJ, Flor AC, Ramamurthy A, Sutton HG, Weichselbaum RR, Kron SJ. Molecular Cancer Therapeutics. 2017 Oct 13. doi: 10.1158/1535-7163.MCT-17-0288.

Radiation-enhanced delivery of systemically administered amphiphilic-CpG oligodeoxynucleotide. Appelbe OK, Moynihan KD, Flor A, Rymut N, Irvine DJ, Kron SJ. Journal of Controlled Release. 2017 Oct 5. doi: 10.1016/j.jconrel.2017.09.043.

Chemical inhibitors of Candida albicans hyphal morphogenesis target endocytosis. Bar-Yosef H, Vivanco Gonzalez N, Ben-Aroya S, Kron SJ, Kornitzer D. Nature Scientific Reports. 2017 Jul 18. doi: 10.1038/s41598-017-05741-y.

Basal tumor cell isolation and patient-derived xenograft engraftment identify high-risk clinical bladder cancers. Skrowron KB, Pitroda SP, Balogun O, Beckett MA, Zenner ML, Fayanju O, Huang X, Fernandez C, Zheng W, Qiao G, Chin R, Kron SJ, Khodarev NN, Posner MC, Steinberg GD, Weichselbaum RR. Nature Scientific Reports. 2016 Oct 24. doi:10.1038/srep35854.

Lipid-derived reactive aldehydes link oxidative stress to cell senescence. Flor AC and Kron SJ. Nature Cell Death & Disease. Invited article. 2016 Sept 8. doi:10.1038/cddis.2016.275.

Image-guided radiotherapy targets macromolecules through altering the tumor microenvironment. Appelbe OK, Zhang Q, Pelizzarri CA, Weichselbaum RR, Kron SJ. Molecular Pharmaceuticals, 2016 Sept 1. doi: 10.1021/acs.molpharmaceut.6b00465

Modulation of therapy-induced senescence by reactive lipid aldehydes. Flor AC, Doshi AP, Kron SJ. Nature Cell Death Discovery, 2016 July 04. ​doi:10.1038/cddiscovery.2016.45.

Repurposing cephalosporin antibiotics as pro-senescent radiosensitizers. Labay E, Mauceri HJ, Efimova EV, Flor AC, Sutton HG, Kron SJ, Weichselbaum RR. Oncotarget, 2016 April 25. doi: 10.18632/oncotarget.8984.

Mps1 Mediated Phosphorylation of Hsp90 Confers Renal Cell Carcinoma Sensitivity and Selectivity to Hsp90 Inhibitors. Woodford MR, Truman AW, Dunn DM, Jensen SM, Cotran R, Bullard R, Abouelleil M, Beebe K, Wolfgeher D, Wierzbicki S, Post DE, Caza T, Tsutsumi S, Panaretou B, Kron SJ, Trepel JB, Landas S, Prodromou C, Shapiro O, Stetler-Stevenson WG, Bourboulia D, Neckers L, Bratslavsky G, Mollapour M. Cell Rep. 2016 Jan 19.

The dynamic interactome of human Aha1 upon Y223 phosphorylation. Wolfgeher D, Dunn DM, Woodford MR, Bourboulia D, Bratslavsky G, Mollapour M, Kron SJ, Truman AW. Data In Brief, 2015 Nov 6. doi: 10.1016/j.dib.2015.10.028.

Acetylation of an NB-LRR Plant Immune-Effector Complex Suppresses Immunity. Lee J, Manning AJ, Wolfgeher D, Jelenska J, Cavanaugh KA, Xu H, Fernandez SM, Michelmore RW, Kron SJ, Greenberg JT. Cell Rep. 2015 Nov 24;13(8):1670-82. doi: 10.1016/j.celrep.2015.10.029

Linking Cancer Metabolism to DNA Repair and Accelerated Senescence. Efimova EV, Takahashi S, Shamsi NA, Wu D, Labay E, Ulanovskaya OA, Weichselbaum RR, Kozmin SA, Kron SJ. Mol Cancer Res. 2015 Nov 4.

c-Abl Mediated Tyrosine Phosphorylation of Aha1 Activates Its Co-chaperone Function in Cancer Cells. Dunn DM, Woodford MR, Truman AW, Jensen SM, Schulman J, Caza T, Remillard TC, Loiselle D, Wolfgeher D, Blagg BS, Franco L, Haystead TA, Daturpalli S, Mayer MP, Trepel JB, Morgan RM, Prodromou C, Kron SJ, Panaretou B, Stetler-Stevenson WG, Landas SK, Neckers L, Bratslavsky G, Bourboulia D, Mollapour M. Cell Rep. 2015 Aug 11;12(6):1006-18. doi: 10.1016/j.celrep.2015.07.004.

Disruption of the lamin A and matrin-3 interaction by myopathic LMNA mutations. Depreux FF, Puckelwartz MJ, Augustynowicz A, Wolfgeher D, Labno CM, Pierre-Louis D, Cicka D, Kron SJ, Holaska J, McNally EM. Hum Mol Genet. 2015 Aug 1;24(15):4284-95. doi: 10.1093/hmg/ddv160.

The quantitative changes in the yeast Hsp70 and Hsp90 interactomes upon DNA damage. Truman AW, Kristjansdottir K, Wolfgeher D, Ricco N, Mayampurath A, Volchenboum SL, Clotet J, Kron SJ. 2014 Nov 7;2:12-5. doi: 10.1016/j.dib.2014.10.006.

Quantitative proteomics of the yeast Hsp70/Hsp90 interactomes during DNA damage reveal chaperone-dependent regulation of ribonucleotide reductase. Truman AW, Kristjansdottir K, Wolfgeher D, Ricco N, Mayampurath A, Volchenboum SL, Clotet J, Kron SJ. J Proteomics. 2015 Jan 1;112:285-300. doi: 10.1016/j.jprot.2014.09.028.

DNA-directed assembly of antibody-fluorophore conjugates for quantitative multiparametric flow cytometry. Flor AC, Williams JH, Blaine KM, Duggan RC, Sperling AI, Schwartz DA, Kron SJ. Chembiochem. 2014 Jan 24;15(2):267-75. doi: 10.1002/cbic.201300464.

DNA resection proteins Sgs1 and Exo1 are required for G1 checkpoint activation in budding yeast. Balogun FO, Truman AW, Kron SJ. DNA Repair (Amst). 2013 Sep;12(9):751-60. doi: 10.1016/j.dnarep.2013.06.003.

The yin and yang of cyclin control by nutrients. Jiménez J, Truman AW, Menoyo S, Kron SJ, Clotet J. Cell Cycle. 2013 Mar 15;12(6):865-6. doi: 10.4161/cc.24217.

Activity assay of epidermal growth factor receptor tyrosine kinase inhibitors in triple-negative breast cancer cells using peptide-conjugated magnetic beads. Ghosh G, Yan X, Kron SJ, Palecek SP. Assay Drug Dev Technol. 2013 Feb;11(1):44-51. doi: 10.1089/adt.2012.454.

CDK-dependent Hsp70 Phosphorylation controls G1 cyclin abundance and cell-cycle progression. Truman AW, Kristjansdottir K, Wolfgeher D, Hasin N, Polier S, Zhang H, Perrett S, Prodromou C, Jones GW, Kron SJ. Cell. 2012 Dec 7;151(6):1308-18. doi: 10.1016/j.cell.2012.10.051.14.

Photocleavable peptide-oligonucleotide conjugates for protein kinase assays by MALDI-TOF MS. Zhou G, Khan F, Dai Q, Sylvester JE, Kron SJ. Mol Biosyst. 2012 Sep;8(9):2395-404.15.

Radiation-inducible immunotherapy for cancer: senescent tumor cells as a cancer vaccine. Meng Y, Efimova EV, Hamzeh KW, Darga TE, Mauceri HJ, Fu YX, Kron SJ, Weichselbaum RR. Mol Ther. 2012 May;20(5):1046-55. doi: 10.1038/mt.2012.19.

Properties of resistant cells generated from lung cancer cell lines treated with EGFR inhibitors. Ghosh G, Lian X, Kron SJ, Palecek SP. BMC Cancer. 2012 Mar 20;12:95. doi: 10.1186/1471-2407-12-95.17.

Strategies and Challenges in Measuring Protein Abundance Using Stable Isotope Labeling and Tandem Mass Spectrometry. Kristjansdottir K, Takahashi S, Volchenboum SL, Kron SJ. Tandem Mass Spectrometry - Applications and Principles. Intech Open, 2012.

Annotator: postprocessing software for generating function-based signatures from quantitative mass spectrometry. Sylvester JE, Bray TS, Kron SJ. J Proteome Res. 2012 Mar 2;11(3):1521-36. doi: 10.1021/pr200460s.

Response of human prostate cancer cells and tumors to combining PARP inhibition with ionizing radiation. Barreto-Andrade JC, Efimova EV, Mauceri HJ, Beckett MA, Sutton HG, Darga TE, Vokes EE, Posner MC, Kron SJ, Weichselbaum RR. Mol Cancer Ther. 2011 Jul;10(7):1185-93. doi: 10.1158/1535-7163.MCT-11-0061.

Ionizing radiation-induced foci persistence screen to discover enhancers of accelerated senescence. Labay E, Efimova EV, Quarshie BK, Golden DW, Weichselbaum RR, Kron SJ. Int J High Throughput Screen. 2011 Mar;2:1-13.

A pairwise chemical genetic screen identifies new inhibitors of glucose transport. Ulanovskaya OA, Cui J, Kron SJ, Kozmin SA. Chem Biol. 2011 Feb 25;18(2):222-30. doi: 10.1016/j.chembiol.2010.12.015.

A magnetic bead-based protein kinase assay with dual detection techniques. Zhou G, Sylvester JE, Wu D, Veach DR, Kron SJ. Anal Biochem. 2011 Jan 1;408(1):5-11. doi: 10.1016/j.ab.2010.08.034.

Photocleavable peptide-conjugated magnetic beads for protein kinase assays by MALDI-TOF MS. Zhou G, Yan X, Wu D, Kron SJ. Bioconjug Chem. 2010 Oct 20;21(10):1917-24. doi: 10.1021/bc1003058.

Quantifying the sensitivities of EGF receptor (EGFR) tyrosine kinase inhibitors in drug resistant non-small cell lung cancer (NSCLC) cells using hydrogel-based peptide array. Ghosh G, Yan X, Lee AG, Kron SJ, Palecek SP. Biosens Bioelectron. 2010 Oct 15;26(2):424-31. doi: 10.1016/j.bios.2010.07.106.

Epigenetic modifications in double-strand break DNA damage signaling and repair. Rossetto D, Truman AW, Kron SJ, Côté J. Clin Cancer Res. 2010 Sep 15;16(18):4543-52. doi: 10.1158/1078-0432.CCR-10-0513.

Poly(ADP-ribose) polymerase inhibitor induces accelerated senescence in irradiated breast cancer cells and tumors. Efimova EV, Mauceri HJ, Golden DW, Labay E, Bindokas VP, Darga TE, Chakraborty C, Barreto-Andrade JC, Crawley C, Sutton HG, Kron SJ, Weichselbaum RR. Cancer Res. 2010 Aug 1;70(15):6277-82. doi: 10.1158/0008-5472.CAN-09-4224.